Over the years, I've toyed around with Painter, ever since it was made by Fractal Design (now developed by Corel), at a few different periods. Its completely different than Photoshop, as it is made to replicate the experience of natural tools and media. Really, it is only worthwhile when combined with a drawing tablet from Wacom. Even though I'm not much of an artist, I find that I can get pretty attractive and interesting results by combining some of Painter's best 'cheater' functions (like cloning colours from a source photo) and my own amateurish brushstrokes with the tablet. For example, I painted this chipmunk from a photo I took of our little visitor on a hike in Whistler a few years back.